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Functional Genomics |
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The genomics era has brought
forth a wealth of information that has revolutionized the way we do science and
has had a large impact in drug discovery. One of the major bottlenecks we face
at the moment is how to establish a link from the genomic information into
function and relevance to disease. Pharmacom intends to integrate database
mining, functional genomics, automation, and bioinformatics to assign function
to novel targets. The effect of genotype on phenotype is poorly understood in
the context of common diseases. However, this understanding promises novel
genomic-based drugs, diagnostics tools, and preventive medicine. We are
developing a comprehensive approach for the genetic dissection of common
diseases by applying DNA pooling to large sample sizes from homogeneous
populations. This allows high-throughput scanning of a large number of SNPs
across the genome on several common diseases. |
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