Nucleic acid ligands against important targets in infectious, malignant and
vascular diseases are continually being discovered by the process of in vitro evolution.
Promising methods are being developed for the exploitation of these aptamers in biosensors
and other diagnostic devices. Ribosome and mRNA display methods for isolating polypeptide aptamers
from highly complex libraries is in development and have the potential to widen the target
range and utility of in vitro evolved ligands.
