There is a wide variety of substances
that may cause allergic reactions in some people. Allergy testing is the
procedure used to determine which particular substances (allergens) are
responsible for provoking an allergic reaction. The procedure used depends on
the type of allergy but may include skin and blood tests or special diets.
Symptoms associated with allergies
Some of the symptoms associated with allergies include:
- Skin rashes - eczema (atopic
dermatitis) or hives (urticaria)
- Swelling - angioedema
- Sneezing and running nose
- allergic rhinitis (hay fever)
- Teary, red, itchy eyes -
allergic conjunctivitis
- Asthma
- Nausea and vomiting -
food allergy
- Anaphylaxis - severe
allergic reaction, which causes serious breathing problems and can be life
threatening.
Medical issues to consider
Before the allergy tests, you need to discuss a range of issues with your
doctor, including:
- Medical history
- Clinical symptoms and when they
occur
- Possible allergen triggers
- Any medicines you take that may
interfere with skin prick test reactions, such as antihistamines.
The procedures
Specific tests are required to determine exactly which substance or substances
are causing the allergy. These tests include:
- Skin prick tests -
selected allergens are applied to the forearm or back with a dropper, and the
skin gently pricked with a needle. A positive result shows within 20 minutes
as a red weal or flare.
- Allergen-specific IgE blood
tests (RAST) - are useful when skin testing is impossible or skin tests
are inconclusive. After a blood sample is taken, the level of
allergen-specific IgE (an immunoglobulin associated with allergic reaction)
produced is measured in a laboratory.
- Elimination diets and
challenge testing - an elimination diet is used to isolate foods that may
be causing an allergic reaction for a particular person. It usually takes a
number of weeks, and involves avoiding foods that have been identified as
common causes of food allergy. No foods or fluids may be consumed other than
those specified in the starting diet. If symptoms improve, foods are added one
at a time until symptoms occur. Usually, a diary is kept to record any
symptoms so they can be linked to the correct food. This procedure must only
be performed under medical supervision.
- Patch tests - are most
commonly used to investigate contact dermatitis. Common triggers include
fragrances (in soaps, for example), nickel (in jewellery, watch buckles and
coins) and chrome (in leathers and bricklayers' cement). The reagents are
available as patches arranged along adhesive strips. The strips are applied to
the back. The area is examined after two and four days. A positive result
shows as redness or blisters at the site of a particular reagent.
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